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Chemical Computing Group Announces the New Release of PSILO®:
A Protein Structure Database System

MONTREAL, Canada, October 29, 2010

Chemical Computing Group (CCG) is happy to announce the release of PSILO version 2010.09. PSILO is a protein structure database system that allows for an integrated repository of proprietary and non-proprietary structural data. With PSILO, experimental and computational macromolecular structural data can be registered, annotated, tracked and shared across organizational departments. PSILO provides powerful bioinformatics and cheminformatics searches with analysis and visualization capabilities through a standard web browser interface.

Some of the new and enhanced capabilities in PSILO 2010.09 are:

  • 3D searches for protein-ligand and protein-protein interactions
  • Faster pocket similarity searching
  • Automatic protein kinase annotation to identify the hinge, HRD motif, G-loop, etc., regions

PSILO's simple yet powerful Google-like search bar allows researchers to apply multiple combinations of text, sequence, 2D substructure and 3D geometry to their search criteria. "We're pleased to announce PSILO 2010.09, a product with superior capabilities than competing protein structure databases in the market" mentioned Paul Labute, president and CEO of CCG. "With PSILO's new powerful 3D search, researchers can now query structural data directly from standard sketchers, facilitating searches for common contacts and other motifs in the protein structure database" added Paul.

PSILO 2010.09 comes with a faster and enhanced pocket similarity search. It automatically maintains a pocket database with an annotated ligand environment. Paul Labute said, "PSILO can search for and score similar binding pockets in dissimilar proteins, allowing organizations to identify cases of convergent evolution and off-target binding, recognizing potential side effects or new possible therapeutic areas."

Another addition in the 2010.09 version is the automatic performance of bioinformatics annotations for all deposited structures: assignment of domain identifiers, Gene Ontology terms, SCOP classes, antibody CDR regions, kinase domain regions and BLAST neighbors. For additional information about PSILO please contact: info@chemcomp.com

About Chemical Computing Group

Chemical Computing Group (CCG) is a leading supplier of software solutions for Life Sciences. CCG has been in business since 1994, always providing state of the art applications in Drug Discovery to Pharmaceutical, Biotech and Academic researcher. CCG's products and services are used by biologists, medicinal chemists and computational chemists throughout the world. Chemical Computing Group has a proven track record in scientific innovation, consistently producing releases and upgrades for all their products. CCG has a very strong reputation for collaborative scientific support, maintaining support offices in both Europe and North America. CCG headquarter is in Montreal, Canada. For more information visit: www.chemcomp.com

For additional information please contact:
Raul Alvarez
Senior Marketing Manager

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