July 02, 2015
||St Johns Innovation Centre|
Cowley Road, Cambridge, CB4 0WS, UK
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Analyzing and Optimizing Protein-Protein Interactions
The course covers tools in MOE for analyzing protein-protein interactions, such as molecular surfaces and non-bonded contact visualization in 3D and using 2D interaction diagrams. Examples include calculating surface properties such as electrostatic hot-spots or patches, as well as physicochemical properties such as the isoelectric focusing point and zeta potential. The effect of mutations on protein-protein interactions generated through the protein engineering applications will also be explored.
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